ACTION - 1 - Heparinisation of patients during AAA repair.
https://www.ejves.com/article/S1078-5884(25)00690-2/fulltext This is a really interesting randomised study that looks at whether Activated Clotting Time number directed heparin treatment improves outcomes for AAA repair. Interestingly, and in common with many other studies of "treating the numbers", there was no benefit in carefully guiding the anticoagulation. 249 patients were included - a healthy amount - and in fact the intensive treatment increased the risk of bleeding and deaths. Definitely worth a read, and finally the old equation of IV heparin dose = 5000U / patient's weight * patient's weight, has evidence!
